|
Jim
Mansfield Spectroscopic
Arthritis Skin Oxygenation
Imaging Works of Art
Personal |
|
|
|
James R. Mansfield Welcome to my web site.
The focus of my work over the last decade or so has been on the application
of spectroscopic methods to medicine. This has involved projects as wide
ranging as the diagnosis of cancer by mid-infrared spectroscopy or the early
diagnosis of rheumatoid arthritis using near-infrared spectroscopy, to
several hyperspectral (or spectral or multispectral, depending on which
nomenclature you prefer) imaging applications. Many of the pages are not
complete, but I hope to have some time to finish them soon. I’ve recently
been working on the NIR Imaging of Art and the Spectroscopic Imaging Hardware pages,
so you might want to have a look. I am the Product
Manager, MSI Systems and Senior Spectral Imaging Scientist at Cambridge
Research & Instrumentation (CRi, www.cri-inc.com),
where I am working on product development and management of their line of
multispectral imaging systems. One is for microscopic applications (Nuance) and the other
is for small animal imaging (Maestro). CRi is the
manufacturer of liquid crystal tunable filters (LCTFs), which are used in a
large number of spectral imaging devices, and a variety of other
liquid-crystal related products for a range of applications from telecom to
cell biology. Before starting at CRI,
I was working at a small company called Hypermed,
which I had helped to co-found. Hypermed was formed to do research into and
commercialize many of the skin oxygenation and tissue hydration applications
of hyperspectral imaging that we have developed. While at Hypermed, I also
did some work for Lumen Laboratories
developing a time-resolved fluorescence confocal macro-imaging system and
some data analysis methods to look at some intercalating dye and DNA systems. I worked as the Director of Analysis at Argose, Inc. for three years. Argose is a medical device company developing a noninvasive glucose-monitoring device that uses a proprietary skin autofluorescence methodology. There I managed a group of 8 scientists and mathematicians working on a methodology for making clinically useful non-invasive glucose measurements. Before that, I worked
at the Institute for Biodiagnostics, a
part of the National Research Council of Canada,
where I first began using spectroscopic methods for medical applications.
During my 8 years at the NRC, our group was focusing on developing medical
diagnostic methods using spectroscopy. I was working in three major areas:
development of a hyperspectral imaging system and its applications in
medicine; non-invasive diagnosis and monitoring of disease (rheumatoid
arthritis and basal cell carcinoma); and non-subjective classification of
ex-vivo cancer spectra. In general, pretty much all of the projects on which I have worked have involved some form of optical spectroscopy (mid-infrared, near infrared, visible, Raman and fluorescence), in either imaging or non-imaging modes, and the application of multivariate statistical methods (aka chemometrics) to the analysis of the spectra. Contact Info: James R.
Mansfield Created
by Jim Mansfield. Last Update:
July 3, 2005 All rights reserved. |